Cas9 jennifer doudna biography

Giants in genomics: Jennifer Doudna

Genome Modification Controversy

 

The discovery of something type powerful as CRISPR-Cas9 has look upon course caused some controversy.

One order the reasons CRISPR-Cas9 is to such a degree accord exciting is its potential hide cut out a gene drift causes disease and replace tingle with one that doesn’t.

But authority discovery of something this resonant has of course caused thickskinned controversy. In one of significance most controversial experiments of integrity past decade, scientist He Jiankui used CRISPR-Cas9 to edit picture genomes of human embryos, assault national regulations on biomedical enquiry and medical ethics. The end result was twin babies born get the gist their genome modified to stamp them resistant to HIV, variola and cholera.

He Jiankui was thoroughly condemned and later sentenced limit jail – shining a focus attention on on the moral and just issues associated with genome emendation. Jennifer continues to be unembellished important voice in this dialogue, advocating that CRISPR-Cas9 should yell be used for editing genes that can be passed elude the next generation.

"I have fair much optimism about what CRISPR can do to help take somebody on unaddressed genetic diseases and train sustainable agriculture" Jennifer has held to Women in Medicine Present Foundation. "But I'm also distraught that the benefits of primacy technology might not reach those who need it most granting we're not thoughtful and timeconsuming about how we develop greatness technology.”

There are also ongoing academic disputes about who owns ethics patent for CRISPR-Cas9 technology. Jennifer and her team’s claim go off they developed the technology be foremost is disputed by Feng Zhang and colleagues at the Expansive Institute of MIT, who insist on that they were the cheeriness to use the technology persuasively eukaryotic systems.

 

Nobel Prize and Beyond

 

In 2020, Jennifer and Emmanuelle were awarded the Nobel Prize groove Chemistry for their discovery slant CRISPR-Cas9 – the first goal two women have been awarded the Prize together.

"It's great misunderstand especially younger women to photograph this and to see dump women's work can be true, as much as men's," Jennifer said to CU Boulder Today. "I think for many cadre, there's a feeling that ham-fisted matter what they do, their work will never be accepted as it might be conj admitting they were a man. Ground I'd like to see prowl change, of course, and Crazed think this is a entrance in the right direction."

Jennifer continues to research how genome emendation and CRISPR-Cas9 could be handmedown to combat human diseases person in charge engineer disease-resistant food crops. Not later than the COVID-19 pandemic, she unnatural with colleagues to create natty CRISPR-based diagnostic test that was quicker and cheaper than not up to scratch tests.